Erratum: A new family of ATP-dependent oligomerization-macrocyclization biocatalysts

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A new family of ATP-dependent oligomerization-macrocyclization biocatalysts.

Oligomerization and macrocyclization reactions are key steps in the biosynthesis of many bioactive natural products. Important macrocycles include the antibiotic daptomycin (1; ref. 1), the immunosuppressant FK-506 (2; ref. 2), the anthelmintic avermectin B1a (3; ref. 3) and the insecticide spinosyn A (4; ref. 4); important oligomeric macrocycles include the siderophores enterobactin (5; ref. 5...

متن کامل

Baeyer-Villiger monooxygenases, an emerging family of flavin-dependent biocatalysts

Baeyer-Villiger monooxygenases (BVMO) are flavoenzymes that catalyze a remarkably wide variety of oxidative reactions such as regioand enantioselective Baeyer-Villiger oxidations and sulfoxidations. Several of these conversions are difficult to achieve using chemical approaches. Due to their selectivity and catalytic efficiency, BVMOs are highly valuable biocatalysts for synthesis of a broad ra...

متن کامل

Microtubule disassembly by ATP-dependent oligomerization of the AAA enzyme katanin.

Katanin, a member of the AAA adenosine triphosphatase (ATPase) superfamily, uses nucleotide hydrolysis energy to sever and disassemble microtubules. Many AAA enzymes disassemble stable protein-protein complexes, but their mechanisms are not well understood. A fluorescence resonance energy transfer assay demonstrated that the p60 subunit of katanin oligomerized in an adenosine triphosphate (ATP)...

متن کامل

A new family of (A, N)-implications: Construction and properties

This paper deals with a new family of (A, N)-implications that derived from fuzzy negation and continuous monotone function, and some properties, like the left neutrally, the exchange principle, the ordering property and the laws of contraposition, of the proposed family of (A, N)-implications are studied. Moreover, the T-conditionality and the Modus tollens for the new family of (A, N)-i...

متن کامل

Fungal Unspecific Peroxygenases: a New Generation of Oxygen-transferring Biocatalysts

The oxygenation of organic molecules is a challenging task in synthetic chemistry and therefore biocatalytic approaches using oxygen-transferring enzymes have come into the focus of chemists and biotechnologists. Fungal peroxygenases represent a unique enzyme type that selectively transfers oxygen from peroxides (R-OOH) to numerous substrates such as benzene derivatives, polycyclic aromatic hyd...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Nature Chemical Biology

سال: 2009

ISSN: 1552-4450,1552-4469

DOI: 10.1038/nchembio0409-266